The component composition of the А. nobilis (Asteraceae) essential oil, which grows in Azerbaijan, was studied for the first time by the gas-chromatography-mass spectrometry method. In the essential oil, 35 components are identified, mainly the terpenoid compounds of which the main constitutes 15: the main components are artemisia ketone (23,7 %), thujone (22,4 %), 2-bornanone (6,4 %), evdesm-7(11)-en-4-ol (6,3 %), eucalyptol (4,5 %), cubenol (3,3 %), lavan-dulol (3,0 %), β-thujone (2,9 %), β-eudesmol (2,7 %), methyl hinokiate (2,1 %), terpinin-4-ol (1,7 %), 1,2-longidione (1,3 %), limonen-6-ol, pivalate (1,2 %), neryll (S)-2-methylbutanoate (1,1%), сaryophyllene oxide (1,0 %). As a result of research the noble yarrow essential it was determined that, essential oil has high antimicrobial activity in attitude Staphylacoccus aureus.
Achillea nobilis L, essential oil, hydrodistillation, gas chromatography-mass spectrometry, antimicrobial activity
1. Flora Azerbaydzhana. Baku, AN AzSSR, 1952. T. 8. S. 265.
2. Kerimli E. G., Serkerov S. V. Issledovanie komponentnogo sostava efirnogo masla Achillea millefolium / E. G. Kerimli, S. V. Serkerov // Suchasnı problemi farmakoterapii I priznachennya lıkars'kih zasobıv. Materiali II Mizhnarodnoi naukovo-praktichnoi konferencii. Harkiv. - 2018. - T. 1. - C. 98-101.
3. Karamenderes C., Karabay Yavasoglu N. U., Zeybek U. Composition and anti-microbial activity of the essential oils of Achillea nobilis L. subsp. sipylea and subsp. neil-reichii / C. Karamenderes, N. U.Karabay Yavasoglu, U. Zeybek // Chemistry of Natural Compounds. - 2007. - Vol. 43 (5). P. 632-63, doi:.org/10.1007/s10600-007-0213-z
4. Liselotte K., Anca M., Enne P., Ursula P. Flavonoids from Achillea nobilis L. / K. Liselotte, M. Anca, P. Enne, P. Ursula // Z. Naturforsch - 2003. - Vol. 58. - P. 11-16, doi:https://doi.org/10.1515/znc-2003-1-202
5. Ahmed A. M., Shar S. A., Mohamed - Elamir F. H. A New Epimeric Sesquiterpene Lactone from Achillea ligustica / A. M. Ahmed, S. A. Shar, F. H. Mohamed-Elamir // Rec. Nat. Prod. - 2012. - Vol. 6 (1). - P. 21-27.
6. Sadyrbekov D. T., Suleimenov E. M., Tikhonova E. V. Atazhanova G. Component composition of essential oils from four species of the genus Achillea growing in Kazakhstan / Sadyrbekov D. T., Suleimenov E. M., Tikhonova E. V. Atazhanova G. // Chem. Nat. Comp. - 2006. - Vol. 42 (3). - P. 294-297, doihttps://doi.org/10.1007/s10600- 006-0102-x
7. Ayoobi F., Shamsizadeh A., Fatemi I. Bio-effectiveness of the main flavonoids of Achillea millefolium in the pathophysiology of neurodegenerative disorders a review / F. Ayoobi, A. Shamsizadeh, I. Fatemi // Iran J. Basic Med. Sci. - 2017. - Vol. 20 (6). - P. 604-612, doi:https://doi.org/10.22038/IJBMS.2017.8827.
8. Nurhayat T., Betül D., Fatih D., İlhan G. Essential Oil Composition of Five Collections of Achillea biebersteinii from Central Turkey and their Antifungal and Insecticidal Activity / T. Nurhayat, D. Betül, D. Fatih, G. İlhan // Natural Product Communications. - 2011. - Vol. 6 (1). - P. 701-706, doi: 10.1177 /1934578X 1100600526
9. Gamal A. S., Hasan Y., Irem T., Rehab F. A., Serap A. A., Galip A. The potential anticonvulsant activity of the ethanolic extracts of Achillea nobilis and Momordica charantia in rats / A. S. Gamal, Y. Hasan, T. Irem, F. A. Rehab, Serap A. A., Galip A. // Journal of Pharmacy & Pharmacognosy Research. - 2016. - Vol. 4 (3). - P. 107-114.
10. Ghasemi Y., Khalaj A., Mohagheghzadeh A., Khosaravi A. Composition and in vitro antimicrobial activity of the essential oil of Achillea eriophora / Y. Ghasemi, A. Khalaj, A. Mohagheghzadeh, A. Khosaravi // Chem. Nat. Somp. - 2008. - Vol. 44(5). - P. 663- 665, doi:https://doi.org/10.1007/s10600-008-9160
11. Chalchat, J.C., Gorunovic, M.S., Petrovic, S.D. Aromatic plants of Yugoslavia. I. Chemical composition of oils of Achillea millefolium L. ssp. Pannanica (Scheele) Hayak, A. crithmifolia W. et K., serbica Nym. and A. tanacetifolia ali. / J.C. Chalchat, M.S. Gorunovic, S.D. Petrovic // Journal of Essential Oil Research. - 1999. - Vol. 11(3). - P. 306-310, doi:org/10.1080/10412905. 1999.9701140
12. Kücükbay, F.Z., Kuyumcu, E., Arabaci, T. The essential oil of Achillea boissieri Hausskn. ex Boiss./ F.Z. Kücükbay , E. Kuyumcu, T. Arabaci // Chemistry of Natural Compounds. - 2010. - Vol. 46 (25). - P. 824-825, doi: 10.1007/ s10600-010-9758-3
13. Rustaiyan A., Komeilizadeh H., Shariatpanahi, M.S., Jassbi, A., Masoudi, S. Comparative study of the essential oils of three Achilea Species from Iran. / A. Rustaiyan, H. Komeilizadeh, M.S. Shariatpanahi, A. Jassbi, S. Masoudi // Journal of Essential Oil Research. - 1998. - Vol. 10 (2). - P. 207-209.
14. Simic N., Andjelkovic, S., Palic, R., Vajs, V., Milosavicevis, S. Composition and antibacterial activity of Achillea chrysacoma essential oil / N. Simic, S. Andjelkovic, R. Palic, V. Vajs, S. Milosavicevis // Journal of Essential oil Research. - 2000. - Vol. 12 (6). - P. 784-787.
15. Nemeth E. Essential oil composition of species in the genus Achillea / E. Nemeth // Journal of Essential Oil Research. - 2005. - Vol. 17(5). - P. 501-512, doi:https://doi.org/10.1080/10412905.2005.9698978
16. Demirci, F., Demirci, B., Gürbüz, I., Yesilada E., Baser K.H.C. Characterization and biological activity of Achillea teretifolia Willd. and A. nobilis L. subsp. neilreichii (Kerner) formanek essential oils / F. Demirci, B. Demirci, I. Gürbüz, E. Yesilada, K.H.C. Baser // Turkish Journal of Biology. - 2009. - Vol. 33 (2). - P. 129-136, doihttps://doi.org/10.3906/biy-0808-1
17. Kürkcüoglu M., Tabanca, N., Ozek T. The essential oil of Achillea falcata L. / M. Kürkcüoglu, N. Tabanca, T. Ozek // Flavour and Fragrance Journal. - 2003. - Vol. 18 (3). - P. 192-194.
18. Baser K.H.C., Demirci, B., Demirci F., Kocak S., Akinci, C., Malyer, H., Guleryuz, G. Composition and antimicrobial activity of the essential oil of Achillea multifida / K.H.C. Baser, B. Demirci, F. Demirci, S. Kocak, C. Akinci, H. Malyer, G. Guleryuz // Planta Medica. - 2002. - Vol. 68 (10). - P. 939-941, doi:https://doi.org/10.1055/s-2002-34923
19. Aslan S., Evren H., Konuklugil, B., Turkoglu, I., Kartal, M. Essential oil composition of Achillea teretifolia from Turkey. - Chemistry of Natural Compounds. - 2009. - Vol. 45(2). - P. 274-275. doi: org/10.1007/s10600-009-9276-3
20. Chandler R.F., Hooper S.N., Harvey N.J. Ethnobotany and phytochemistry of yarrow, Achillea millefolium, compasitae. / R.F. Chandler, S.N. Hooper, N.J. Harvey // Economic Botany. - 1982. - Vol. 36 (2). - P. 203-223.
21. Abdul Hafiz I. Y., Egorov M. A., Suhenko L. T. Antibakterial'naya aktivnost' efirnogo masla spirtovyh ekstraktov aira blotnogo (Acorus calamus) i verblyuzh'ey kolyuchki (Alhagi pseudalgahi), sobrannyh v Astrahanskoy oblasti / I. Y. Abdul Hafiz, M. A. Egorov, L. T. Suhenko // Vestnik Altayskogo gosudarstvennogo agrarnogo universiteta. - 2011. - №3 (77). - C. 50-53.
